VI-28 - A Natural Anti-aging Health Supplement

Humans have been looking for differents ways to achieve longevity. In both Eastern and Western society, from ancient ages to nowadays, humans always want to discover or invent something which could achieve immortal.

In the past 10 years, due to the rapid developments of Western medical technology, the development of longevity medicine has gained a great leap. Although it is impossible to become immortal, many Western medical experts and scientists agreed on the "anti-aging theory" and the "anti-aging" medicines indicated that we may achieve the goal of longevity.

Combination of Chinese and Western Medicine

Although the history of Chinese medicine was more than 5000 years, it was not developed well like the Western medicine. However, since there were many exchanges between Chinese and Western medicines in recent years, Chinese medicine is now re-vitalized. The combination of Chinese and Western medicines has become a new trend. Medical scientists do lots of scientific researches on Chinese medicines so as to find better therapeutic medicines.

Vigconic (International) Limited, a Hong Kong-based company, started researches on "anti-aging" natural medicines since 1998. In order to evaluate the efficacy of our newly-invented "anti-aging" Chinese medicine, VI-28, Vigconic decided to carry out researches by the approach of Western medical science. The researches were started from Pharmacology, followed by animal tests, and finally tested clinically in humans. Scientific methods were used to confirm VI-28's efficacy. By using specific protocols, scientists and researchers discovered a surprising result. They found that VI-28 can achieve the same efficacy as Western "anti-aging" medicines but its price is just 5% of Western counterparts.

Before we talk about the anti-aging efficacy of VI-28, let see the aging of human in western medical perspective.

HGH and IGF-1: Key Factors of Aging

Human body is made up of more than one trillion of cells, each cell works hard all the time. The driving force of body cells is "Hormone". Hormone is secreted from various organs including pituitary gland, adrenal gland, thyroid gland, etc. Upon receiving the signals from the brain, hormone is secreted and delivered to the cells via blood stream.

Human Growth Hormone (HGH) is a hormone secreted from the pituitary gland. Its purpose is to help the growth of cells. When HGH reaches liver, it stimulates the liver to secrete Insulin-like Growth Factor-1 (IGF-1), which is then converted to many different essence of growth. At the time of bone growing of children, their body secretes high level of HGH, which makes different organs grow. During the puberty, HGH secretion is at its maximum level. When humans reach middle-age, HGH secretion from the pituitary gland gradually declines.

There are researches which pointed out HGH could slow down the aging of cells. The aging of cells is due to the DNA attacks by oxidative free radicals. This phenomenon may seem inevitable because oxidative free radicals are side-products of the process of cells' growth. HGH is a key factor to terminate "Programmed Cell Death". Every cell has a pre-determined time of death. When human is at middle-age, the number of cell death is higher than that of cell growth, this indicates the beginning of aging. HGH in turn stimulates the cell protein enzyme inhibitors to prevent "Programmed Cell Death".

Workflow of VI-28

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Decline of HGH Level

IGF-1 level is a usual indicator of HGH level in our body. The amount of HGH secretion is different over a day, the HGH secretion is the highest during mid-night while it is relatively low at other times. This amount and secretion pattern also varies a bit among different people. Therefore, it is difficult for scientists to measure the HGH level and its patterns. However, IGF-1, the secretion stimulated by HGH, shows an even and sustained secretion pattern. Therefore scientists estimate HGH level by measuring IGF-1 level.

Discovery of HGH

Researches have shown that HGH secretion reaches maximum at the age of 20, and declines year by year afterwards. At the age of 50 to 60, the secretion is just about 30% of the maximum. To counteract with the decline of hormones, the Western medicine currently uses gene-recombinant technology to extract DNA from cells secreting growth hormone and put it into the cells of human chest, which then divide and multiply quickly. On 5 July 1990, Dr. Daniel Rudman of the Faculty of Medicine, State University of Wisconsin, US, published his famous research paper on the New England Journal of Medicine, an important medical journal in the world. His research involves the clinical study of HGH on 12 human of age higher than 60. After 6 months, he carried out tests on the subjects and the results showed HGH could achieve "anti-aging"effect.

So, the Western medical doctors perceived HGH as the key factor to "anti-aging". Numerous researches on "anti-aging" were then started.

Scientists estimate that the effective use of HGH could lengthen one's life to 120-140 years old, which of course is not the age of "sitting on the wheelchair and grumbling, or being bored to death in elderly's home", but the age of being healthy, energetic and living with dignity. However, the price to achieve anti-aging is very high. Since the manufacturing of HGH is very difficult and people should consult with special consultants or doctors during receving the medicine, a half-yearly therapy could cost about HK$100,000. It means "anti-aging" therapy is just for the rich.

Relationship between VI-28 & HGH

VI-28, a pure Chinese medicine manufactured by Vigconic (International) Limited, stimulates the secretion of HGH from the regressing pituitary gland. It contains Chinese medicines such as Radix Ginseng, Cornu Cervi Pantotrichum (the cartilaginous part of root of antler), Fructus Cnidii, etc. The "anti-aging" effect of VI-28 is proved by scientific researches. In Anti-Aging World Conference held in February 2003, the initial clinical research reports of VI-28 was presented by Dr. S.H. Chui, Chairman of the Asian Anti-Aging Association and Professor K.M. Ko of the Department of Biochemistry, The Hong Kong University of Science and Technology.
The research involved a 12-week use of VI-28 in 25 healthy males, age 51-66, who were observed for anti-aging efficacy of VI-28. All subjects were examined by both physicians and Chinese medical practitioners every month, and their blood samples was tested for biochemical, immunological, homeostatic and anti-oxidizing indicators tests. More than 75% of the subjects felt significant improvement in their sexual function and body strength, reduction in night-time urination, improvement in quality of sleeping. The doctors also found no side effects on subjects' functions of liver, kidneys and circulatory system. The report was presented as the followings.

Scientific Research proved VI-28's efficacy in anti-aging

The previous clinical research showed that VI-28 could regulate cholesterol metabolism and balance endocrine system, and therefore improve body immune function and anti-oxidizing functions of bloodstream, thereby delay aging process.

Research Findings of VI-28

Remarks:

* Use VI-28 for 4 weeks
**Use VI-28 for 12 weeks
P-value < 0.05 indicates significant change

The above results showed there was a 32% increase in IGF-1 by using VI-28 for 12 weeks, indicating increase in HGH. Althoughh VI-28 is not a Western synthetic HGH, it can achieve the same anti-aging effect. It directly stimulates the pituitary gland of middle-aged people to increase its secretion of HGH.

Also, for those using VI-28, the red blood cell superoxide dismutase (SOD) level was increased by 63%. The main function of SOD is to clear out oxidative free radicals, the side-product of cell growth. Oxidative free radicals will destroy DNA and RNA of cells and slows down cell growth. The increase in SOD means the decrease in oxidative free radicals, so the condition of "cell death" is improved. The increase in plasma's clearing of DPPH free radicals also indicates the same improvement. The rise in the number of CD4 and CD8 immune cells indicates the strengthen of immune function of the subjects.

Thymus Gland and Immune Function

The number of lymphocyte T-Cells in human body decreases gradually with age, especially the CD4 T-Helper cells and the CD8 Killer cells. Thymus is an important organ in immune system. Its function is to produce and stimulate the maturity of T-cell lymphocytes. T-cells are the most important in the body against diseases. HGH can re-vitalize the aging thymus and more T-lymphocytes can be produced.

Anti-aging" scientists also discovered the close relationship between thymus and the lifespan of human. Thymus is located behind the thoracic bone. Its size increases from 15g (at the infant stage) to the maximum during puberty. However, thymus's size starts to decrease after puberty. At the age of 50-60, thymus has shrunk to as small as a dried grape.

According to rules in animal (including human) biology, human lifespan should be about 5-7 times of sexual development stage. For example, 18 years old is the sexual mature stage in human, so humans should theoretically live up to 100-120 years. However, most people can only live up to 70 years old. The ultimate cause for the shorter lifespan is the reduction of size of thymus, leading to declined immune system and functions. When facing various diseases, humans become old prematurely and their lifespan shortens.

The following graph shows the size of thymus of old mice after using VI-28, the study was carried out by Prof. Xiao Ming Gao, Director of College of Fundamental Medicine, Faculty of Medicine, Peking University.

VI-28 Progress Table